Aloette’s Age Defiance Pro Firming Serum with Restoracell does connect itself with some level of science and technology. The site talks about enabling the body to naturally produce collagen for years to come by using sirtuin activators. In scientific terms, sirtuins have been connected to common signs of aging as well as to age related disorders such as Parkinson’s disease and Type 2 diabetes. Sirituin activity is normally blocked by nicotinamide. Drugs and other elements such as the resveratrol found in red wine(in high amounts generally not found in red wine)can inhibit the activity of nicotinamide and therefore allow the sirtuins to act more freely and reduce and prevent some signs of aging. The site also provides a complete list of ingredients, one of which was pamitoyl oligopeptides, another name for matrixyl. Preliminary studies have shown matrixyl to possibly stimulate collagen, elastin, and glucoasmoglycans, and repair sun damage as well are retinol, but without the negative side effects. Aloette as a company also does not test on animals, most likely partly due to the fact that animal studies often do not carry over to human subjects.

I found quite a bit of information on the website and across the web. But there were also quite a few things I did not find. To start, I did not find any information on restoracell technology. They emphasize its use, but they don’t take the time to explain what it actually is. It seems to be a technology specifically patented by Aloette, because no one else uses it and there is no information to be found anywhere else either. The second thing that failed to be there is any ingredients that would contribute to the increased abilities of sirtuins. The ideas and studies involving sirituin are innovative and effective, but in order to implement them, an ingredient such as resveratrol has to be used in a high amount. Aloette does not use ingredients that would contribute to this cause at all. Third, while studies on the effects of matrixyl are promising, the studies are preliminary and have not been officiated in any legitimate clinical trials as of yet. Besides matrixyl, I see a lot of thickeners, emollients, moisturizers, solvents, one muscle relaxant, and one PH balancer. But I see no other ingredients proven or even thought to promote the reversal of certain signs of aging. Aloette obviously saw this discrepancy as well, as their statistics were put under a “56 day test.” Notice they did not call it a clinical trial. They did not boast of it being double blind, randomized, or placebo controlled. Nor did they mention anything about statistically significant differences or any lab where this “test” may have been conducted.

While Aloette’s Age Defiance Pro Firming Serum with Restoracell uses scientific terms and concepts to back up some claims that their serum will reduce certain signs of aging, they don’t actually legitimize any of these claims by following them. Using sirtuin activators is a novel idea, but only when there are ingredients to act as those activators. What I see when I look at this produce is a glorified and overly hyped moisturizer.