#1 Recommended Wrinkle Cream of 2015

Oxytokin by Synergistic Nutritional Compounds

Oxytokin bottle

Expert Rating:

Consumer Rating:

Retail Price: $99.99

Best Price We Found:

$39.95 @


Oxytokin has been the best-selling wrinkle cream for close to five years. This peptide-packed formula is guaranteed to help you look years younger. Oxytokin is the most affordable and powerful wrinkle cream available!

Click Here to Learn More


SplendyrSplendyr is an anti-aging face mask designed to turn back the clock.

Photographs on the official website show women with exaggerated wrinkles next to flawless models, showing the results you can expect from using Splendyr.

Splendyr contains some interesting ingredients.

Let’s take a closer look at what comprises Splendyr’s formula.


Splendyr consists of a combination of synthetic and natural ingredients.

DMAE (2-dimethylaminoethanol)

DMAE is used to increase skin firmness. In one clinical trial, DMAE decreased the appearance of wrinkles, sagging neck skin, and under-eye dark circles. [1]

MSM (Methylsulfonymethane)

MSM reduces skin redness and uneven texture associated with rosacea. One study showed patients experienced improved color and hydration and decreased itching and papules after using topical MSM for 1 month. [2]

Lipoic Acid

In one clinical study, lipoic acid seemed to be a potential solution to thinning skin. The study used lipoic acid to increase collagen production in rat skin. The results may be reproduced in human skin. [3]

Hyaluronic Acid

This substance is naturally produced in human skin. It is a potent moisturizer that is also used to heal burns and wounds. [4]


Found naturally in grape and wine extracts, resveratrol is a powerful antioxidant. In one study, resveratrol showed promise as an acne treatment. Subjects saw a 66.7% decrease in breakouts after 60 days using a topical gel with resveratrol. [5]

Jojoba Oil

This oil is a moisturizer. It also soothes damaged skin, making it a good treatment for skin that is acne-scarred, chapped, or sunburnt. [6]

Coenzyme Q10

This compound shows promise as a UV radiation protector. It is an antioxidant that prevents damage done by free radicals. [7]

Vitamin E

This vitamin is an antioxidant. It has been used as a sunblock in studies, preventing damage done by free radicals and UV rays. [8]

About Splendyr’s Parent Company

Splendyr is owned by Clear Skin, LLC headquartered in Salt Lake City, Utah. According to the Better Business Bureau, Clear Skin has garnered 37 complaints over the last 12 months. This earns the company an F rating, the lowest the BBB awards.

Most complaints have to do with the free trial offer which is heavily advertised on the official website. Although the website clearly states ordering a free trial enrolls the purchaser in an auto-ship program, most customers do not read the fine print before ordering. As a result, the miscommunication causes problems among customers.

It should be noted there are no complaints listed about the quality of the product. Customers are so focused on their experiences with customer service that most of them don’t review Splendry at all.

Free Trial Offer

The Splendyr website only offers the anti-aging face mask as a free trial. There are no prices listed.

When a customer orders a free trial, they enroll themselves in an auto-ship program, which mails a new package of the product at regular intervals. The website does not specify how often the product is sent or how much is charged for each shipment.

To cancel the auto-ship program, click the “Easy Cancel” button on the “Customer Service” tab. Follow the instructions as they are presented by the company, and the shipments and charges should cease.

Buy or Bust?

Splendyr may be a fine product. However, with all the customer complaints about customer service, there is little opportunity for a potential customer to evaluate the product. I recommend finding a third party retailer of Splendyr rather than dealing directly with the company.

However, since there are so few reviews of Splendyr as a product, I recommend waiting for more information about the product before purchasing. Right now there is simply not enough information available to make an educated purchase.


[1] Grossman R. “The role of dimethylaminoethanol in cosmetic dermatology”. American Journal of Clinical Dermatology. 2005;6(1):39-47. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15675889

[2] Berardesca E, Cameli N, Cavallotti C, Levy JL, Pierard GE, De Paoli Ambrosi G. “Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluation.” Journal of cosmetic Dermatology. Mar 2008; 7(1):8-14. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18254805

[3] Han B, Nimni M. “Transdermal Delivery of Amino Acids and Antioxidants Enhance Collagen Synthesis: In Vivo and In Vitro Studies.” University of Southern California Keck school of Medicine. 2005, Vol.46, No. 4-5, Pp 251-257. Available from: http://informahealthcare.com/doi/abs/10.1080/03008200500416716

[4] “Hyaluronic Acid”. WebMD. Available from: http://www.webmd.com/vitamins-supplements/ingredientmono-1062-HYALURONIC%20ACID.aspx?activeIngredientId=1062&activeIngredientName=HYALURONIC%20ACID

[5] Fabbrocini G, Staibano S, De Rosa G, Battimiello V, Fardella N, Ilardi G, La Rotonda MI, Longobardi A, Mazzella M, Siano M, Pastore F, De Vita V, Vecchione ML, Ayala F. “Resveratrol-containing gel for the treatment of acne vulgaris: a single-blind, vehicle-controlled, pilot study.” American Journal of Clinical Dermatology. 2011 Apr 1;12(2):133-41. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21348544

[6] “Jojoba”. WebMD. Available from: http://www.webmd.com/vitamins-supplements/ingredientmono-618-JOJOBA.aspx?activeIngredientId=618&activeIngredientName=JOJOBA

[7] Hoppe U, Bergemann J, Diembeck W, Ennen J, Gohla S, Harris I, Jacob J, Kielholz J, Mei W, Pollet D, Schachtschabel D, Sauermann G, Schreiner V, Stab F, Steckel F. “Coenzyme CoQ10, a Cutaneous Antioxidant and Energizer”. BioFactors Journal. Available from: http://iospress.metapress.com/content/97edt1twwxnc5jrd/

[8] Goldfaden R, Goldfaden G. “Skin Protection Effects of Vitamin E.” Life Extension Magazine. Aug 2012. Available from: http://www.lef.org/magazine/mag2012/aug2012_Skin-Protection-Effects-Of-Vitamin-E_01.htm

Have you used Splendyr? Click Here to share your opinion with others or Click Here to read Splendyr customer reviews.

Have You Used Splendyr? Post a Review!