Wrinkless Cream

May 17th, 2013

No Photo Available The official website for Wrinkless Cream claims you can look ten to fifteen years younger in just five seconds after using the product.

While this claim may be a bit over the top, perhaps Wrinkless Cream really can reduce wrinkles and skin aging better than other products. It definitely piqued my curiosity, so I looked a bit further into Wrinkless Cream to get the lowdown on this wrinkle cream.

Wrinkless Cream Claims

Wrinkless Cream manufacturers claim their product does the following:
• Removes deep wrinkles and lines
• Eliminates age spots and blemishes
• Lifts and firms
• Brightens dark circles
• Removes puffiness
• Hydrates skin

Perhaps examining ingredients will give us an idea as to whether Wrinkless Cream really does what the company says it does.

Wrinkless Cream Ingredients

Wrinkless Cream contains 21 natural ingredients. Let’s look at some of the key ones:

Winter Cherry Extract. Winter cherry extract stopped collagen degradation and facilitated collagen stabilization in one study. [1] Since collagens are the proteins that make up skin tissue, stabilizing them could prevent skin breakdown.

Brahmi. Brahmi contains active components that promote wound healing. Topical administration also increases collagen synthesis. [2] However, there is no clinical evidence that brahmi reduces skin aging.

Aloe Vera. Aloe vera reverses skin aging by stimulating collagen and elastin synthesis. [3] It also heals facial wounds and inhibits skin inflammation, which may improve skin appearance. [4]

Sesame Seed Oil. In a preliminary study, sesamol, an antioxidant in sesame seed oil, countered UV-induced stress in mouse skin. [5] This shows potential (but not indefinite proof) of its ability to prevent damage from free radicals and reduce wrinkles and skin aging.

Clove Oil. Clove oil administered topically may relieve pain and promote healing. However, it is also cytotoxic and may damage skin cells. [6]

While these ingredients demonstrate some skin healing properties, there is not enough evidence to suggest that they will perform all the functions manufacturers claim it will.

Wrinkless Cream may hydrate and heal the skin, but the ingredients are not proven to brighten dark circles, remove puffiness, or eliminate age spots. The ingredients may prevent future wrinkles and aging, but it’s unclear how well they can reduce what is already there.

Wrinkless Cream Manufacturers

The makers of Wrinkless Cream are an internet cosmetic company known as Ojas Enterprises, LLC. Although there is little information available about the company, we can assume it is rather unreliable by looking at business websites.

For example, the Better Business Bureau has recorded 33 complaints from customers against Ojas Enterprises and their products. RipoffReport.com also has a complaint from a customer who said they did not get a refund from a canceled free trial order.

Purchasing Wrinkless Cream

Wrinkless Cream can only be purchased via the official website at WrinklessCream.com. But this may prove difficult.

The website claims that it offers a free trial. However, if you do not cancel within fifteen days of purchase, you will be charged $49.95 for the product.

The company also claims that there is no long-term commitment. However, based on customer complaints, I assume that when you sign up for the free trial, you automatically commit to being placed in the monthly auto-ship program. You will be charged $49.95 a month for a new supply of Wrinkless Cream unless you cancel the program.

This makes ordering Wrinkless Cream seem daunting indeed.

Wrinkless Cream: A Deal or a Dud?

Wrinkless Cream might reduce wrinkles. But there’s just not enough evidence to say that it’s as effective as the company claims, and definitely none to support that it’s worth the cost of $49.95 a month.

Due to the unproven nature of the product and the unreliability of the company, avoid Wrinkless Cream and choose a trustworthy wrinkle cream that’s proven to work.

References

[1] Krishnamoorthy Ganesan et al. “Protective Effect of Withania somnifera and Cardiospermum halicacabum Extracts Against Collagenolytic Degradation of Collagen.” Applied Biochemistry and Biotechnology. 2011; 165 (3-4): 1075-1091. Available from: http://link.springer.com/article/10.1007/s12010-011-9326-8

[2] Rajinder Raina et al. “Medicinal Plants and their Role in Wound Healing.” Online Veterinary Journal. 2008; 3 (1). Available from: http://www.kashvet.org/medicinal_plants_wound_healing.html

[3] Ivan E. Danhof. “Potential reversal of chronological and photo-aging of the skin by topical application of natural substances.” Phytotherapy Research. 1993; 7 (7): S53-S56. Available from: http://onlinelibrary.wiley.com/doi/10.1002/ptr.2650070716/abstract

[4] David RH et al. “Anti-Inflammatory & Wound Healing Activity Of A Growth Substance In Aloe Vera.” J Am Podiatr Med Assoc. 84 (2): 77-81. Available from: http://hclux.com/DATA/PDF/PDF_e/CLINICAL%20ABSTRACTS%20-%20Single%20Chapters/05_Wound%20Healing.pdf

[5] Shringi Sharma M., Indu Pal Kaur M. “Development and evaluation of sesamol as an antiaging agent.” International Journal of Dermatology. 2006; 45 (3): 200-208. Available from: http://onlinelibrary.wiley.com/doi/10.1111/j.1365-4632.2004.02537.x/abstract?systemMessage=Wiley+Online+Library+will+be+disrupted+on+18+May+from+10%3A00-12%3A00+BST+%2805%3A00-07%3A00+EDT%29+for+essential+maintenance&userIsAuthenticated=false&deniedAccessCustomisedMessage=

[6] A. Prashar, I.C. Locke, C.S. Evans. “Cytotoxicity of clove (Syzygium aromaticum) oil and its major components to human skin cells.” Cell Proliferation. 2006; 39 (4): 241-248. Available from: http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2184.2006.00384.x/abstract?systemMessage=Wiley+Online+Library+will+be+disrupted+on+18+May+from+10%3A00-12%3A00+BST+%2805%3A00-07%3A00+EDT%29+for+essential+maintenance&userIsAuthenticated=false&deniedAccessCustomisedMessage=

AuraVie

May 16th, 2013

auravie-logo-160AuraVie invites you to put your skin through its “anti-aging skin rejevination regimen,” of five facial products intended to improve skin health and appearance.

Through various natural ingredients, AuraVie promises its products minimize skin imperfections, such as wrinkles and spots.

Can AuraVie’s products really make skin look younger by “defying gravity?” I researched AuraVie’s facial care line to find out.

AuraVie’s Facial Care Line

AuraVie sells five natural treatments said to rejuvenate and protect skin.

REVIVE is AuraVie’s all-in-one serum said to lift, tighten, and hydrate skin. It contains the active ingredient camellia sinensis leaf extract, better known as green tea extract. Thanks to its polyphenol content, green tea is proven to inhibit ultraviolet (UV)-induced cell damage in human fibroblasts, a cell that synthesizes collagen.[1]

In addition, a 2000 clinical study on mouse skin shows green tea also protects cells and tissue against the development of UV-induced cancer cells.[2]

While it appears green tea is an effective tool against photoaging, clinical evidence on its effectiveness has been limited to orally-ingested green tea extract. There is no evidence topical green tea affects skin in a similar fashion.

How to Use It
1. Wash and dry face.
2. Dab small amount on skin
3. Massage gently until almost absorbed into skin.

Pricing
AuraVie.com sells one 1.0 ounce bottle for $99.00. Alternatively, Amazon.com has REVIVE for $74.95.

REFRESH is an acai berry-based facial peel AuraVie claims micro-cleanses and stimulates skin cell growth.

Acai berry contains antioxidant properties that protect cells from damage.[3]

While oral acai berry has health benefits, there is no clinical evidence topical application improves and protects skin cells.

How to Use It
1. Wash and pay face dry.
2. Apply a small amount to skin.
3. Wait for cooling sensation.
4. Then massage in a circular motion.
5. Rewash face with warm, tap water.

Pricing
AuraView.com sells one bottle (1.75 ounces) for $119.99. Amazon.com currently sells it for $72.95.

REVEAL is AuraVie’s facial masque intended to stimulate collagen growth and improve skin density.
Its main active ingredient is silt, or Dead Sea mud. Rich in minerals, silt is proven to protect human skin from photodamage and inflammation.[4]

How to Use It
1. Apply thin even layer to face.
2. Let sit until dry.
3. Massage in circular motion.
4. Remove residue with warm, damp towel.

Pricing
AuraVie.com has one 1.75 ml bottle for $119.99, but it can be purchased cheaper at Amazon.com, where one bottle of REVEAL sells for $54.95

RENEW is a toner/cleanser designed to even skin tone, diminish wrinkles, and fade imperfections.

One of its active ingredients is glycerin, which is proven to hydrate and make skin supple.[5][6]

However, I found no clinical studies implying glycerin evens skin tone or diminishes imperfections.

How to Use It
1. Wet skin.
2. Apply 3 to 6 pumps into palms.
3. Rub hands until foam is produced.
4. Massage foam into skin for 30 seconds.

Pricing
Amazon.com is yet again the better deal; it currently has one RENEW bottle (3 ml) for $21.95. AuraVie.com sells one bottle for $99.00.

REPLENISH is a moisturizer that uses aloe barbadensis (aloe vera) leaf extract to hydrate and revitalize skin. A 2008 clinical study on 40 subjects showed topical aloe vera improved inflammatory skin conditions such as erythema.[7]

How to Use It
1. Wash and pat face dry.
2. Apply a small amount to skin.

Pricing
AureVie.com is currently sells one 1.75 ml bottle for $139.99. Amazon.com has the same product for $74.95.

Are These Products Safe?

Most of the ingredients found in AuraVie’s skin products are safe.

However, there’s always a chance an ingredient causes an allergic reaction. So consult with your dermatologist before using these products if you have sensitive skin.

Does AuraVie Back Its Products With a Guarantee?

AuraVie.com offers a 14-day refund on unopened products, but there is a 15% restocking fee.[8]

Final Thoughts

AuraVie’s skin products may work for you. Many contain ingredients proven to improve skin health and appearance.

However, these same ingredients are found in many skin products, for a more affordable price.

For that reason, you may want to hold off on trying AuraVie – the ingredients don’t appear to justify the products’ high prices.

References

[1] Vayalil, Praveen K., et al. “Green tea polyphenols prevent ultraviolet light-induced oxidative damage and matrix metalloproteinases expression in mouse skin.” Journal of Investigative Dermatology, 122.6 (2004): 1480-1487. http://www.nature.com/jid/journal/v122/n6/abs/5602370a.html

[2] Katiyar, Santosh K., Nihal Ahmad, and Hasan Mukhtar. “Green tea and skin.” Archives of Dermatology, 136.8 (2000): 989. http://archderm.jamanetwork.com/article.aspx?articleid=190508

[3] Mertens-Talcott, Susanne U., et al. “Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers.” Journal of Agricultural and Food Chemistry, 56.17 (2008): 7796-7802. http://pubs.acs.org/doi/abs/10.1021/jf8007037

[4] Portugal‐Cohen, Meital, et al. “Protective effects of a cream containing Dead Sea minerals against UVB‐induced stress in human skin.” Experimental Dermatology, 18.9 (2009): 781-788.Protective effects of a cream containing Dead Sea minerals against UVB-induced stress in human skin

[5] Olsen, L. Overgaard, and G. B. E. Jemec. “The influence of water, glycerin, paraffin oil and ethanol on skin mechanics.” Acta Dermato-Venereologica, 73.6 (1993): 404-406.http://cat.inist.fr/?aModele=afficheN&cpsidt=3851085

[6] Pedersen, L. K., and G. B. E. Jemec. “Plasticising effect of water and glycerin on human skin in vivo.” Journal of Dermatological Science, 19.1 (1999): 48-52.http://www.sciencedirect.com/science/article/pii/S0923181198000504

[7] Reuter, J., et al. “Investigation of the anti-inflammatory potential of Aloe vera gel (97.5%) in the ultraviolet erythema test.” Skin Pharmacology and Physiology, 21.2 (2008): 106-110.http://www.karger.com/Article/Abstract/114871

[8] AuraVie.com. “Return Policy.” Accessed 5.15.2013.https://www.auravie.com/returns.php

Le Derme Luxe

May 10th, 2013

Le Derme LuxeOne of Le Derme Luxe’s many websites offers consumers a chance to claim an exclusive discount jar of this anti-wrinkle cream.

Strangely, though, this webpage says nothing about Le Derme Luxe’s price, discounted or otherwise. To learn Le Derme Luxe’s price, customers are required to input personal information.

Le Derme Luxe’s hidden price makes me wonder about its true value as a wrinkle cream. I investigated Le Derme Luxe to determine if it reduces wrinkles.

How Is Le Derme Luxe Supposed to Affect Skin Health?

Like many anti-wrinkle creams, Le Derme Luxe is said to promote collagen production. Increased collagen improves skin firmness, smoothness, and youthful appearance. Le Derme Luxe’s makers are so confident in this product they says its effects are similar to those of Botox injections.

While the promised effectiveness of Le Derme Luxe sounds good, these claims are all too common for a wrinkle cream. Consequently, other aspects need to be examined to substantiate or disprove these claims.

Who Makes Le Derme Luxe?

Le Derme Luxe is made by a company called Luxury Skin Collection. Luxury Skin Collection is not a well-known cosmetic company. It appears Le Derme Luxe is the company’s only product.

Luxury Skin Collection earns an F rating from the Better Business Bureau. Not revealing background information is one major reason Luxury Skin Collection has this low rating. In addition, Luxury Skin Collection hasn’t responded to several complaints filed with the BBB. Regrettably, this F rating doesn’t reflect positively on Luxury Skin Collection or Le Derme Luxe.

What Ingredients Are in Le Derme Luxe?

Le Derme Luxe uses several ingredients to achieve its advertised effects. Let’s look at those most likely to reduce wrinkles.

Beta Glucan
Beta glucan molecules bolster immunity and reduce inflammation. Continuing research indicates beta glucan also reduces wrinkle size. [1]

Vitamin C Ester
Vitamin C ester has powerful antioxidant capabilities. When applied directly to skin, vitamin C fights inflammation and promotes collagen production. [2]

Alpha Lipoic Acid
As an antioxidant, alpha lipoic acid combats cell damage and improves vitamin levels. Creams containing at least 5% alpha lipoic acid minimizes fine lines. [3] Le Derme Luxe’s alpha lipoic acid concentration is unclear, however.

DMAE
DMAE is a brain chemical linked to decreasing wrinkle appearance. [4] In studies, DMAE creams are proven to increase skin and collagen fiber thickness. [5]

Natural Progesterone PSP
Progesterone is a hormone mainly associated with the female reproductive cycle. A 2005 study showed 2% progesterone cream optimizes skin firmness and elasticity. [6]

Estriol USP
Estriol is another female sex hormone that improves signs of skin aging. Participants using estriol cream in a six-month study showed significant decrease in wrinkle depth and pore size. [7]

Le Derme Luxe’s ingredients seem well-suited for eliminating wrinkles. However, their total efficacy is hard to assess because Luxury Skin Collection hasn’t released ingredient concentrations.

Does Le Derme Luxe Have Any Consumer Reviews?

MySkinMD.info contains comments from three female Le Derme Luxe users. These women claim Le Derme Luxe reduced or eliminated their fine lines and forehead wrinkles. One woman said she noticed results in just a few days and some of her wrinkles have yet to reappear.

These women’s comments suggest Le Derme Luxe is an effective wrinkle cream. However, three women are hardly a sufficient sample size to guarantee results for most women.

How Do You Use Le Derme Luxe?

The directions for using Le Derme Luxe are straightforward. Simply wash and dry your face before massaging the cream into your wrinkles.

But, the usage directions don’t state how many times a day Le Derme Luxe can be used. It’s not a big deal, but it’s nice to know if a product is safe to use multiple times throughout the day.

Similarly, there is also no indication of the best time of day to apply Le Derme Luxe. Some products are most effective when used in the morning or at night. For others, it makes no difference. It would be nice to know this information about Le Derme Luxe.

How Much Does a Le Derme Luxe Jar Cost?

It takes some digging to uncover Le Derme Luxe’s price. This is because no Le Derme Luxe website I came across prominently lists the price.

After inputting some personal information, I was taken to a checkout page. According to this page, the first jar of Le Derme Luxe costs only $4.95.

But, if customers do not cancel future orders within 14 days of their first purchase, they are automatically enrolled in a membership program. This membership program ensures customers are shipped a new jar of Le Derme Luxe every 30 days. Each Le Derme Luxe jar in this membership program costs between $75 and $90, depending on where the initial purchase took place. Customers have to sign up for either a 3-month or a 6-month membership. They cannot order just one jar at a time.

If people like the effects of Le Derme Luxe, this membership program eliminates the hassle of ordering every month. But, I’m always wary of a company that makes customers agree to buy multiple bottles just to buy one.

Is It Possible to Return Le Derme Luxe?

Luxury Skin Collection has a 30-day return policy, so Le Derme Luxe can be returned.

However, only unopened, unused jars are eligible for return. In other words, once you open your jar of Le Derme Luxe to try it, you cannot return it. Instead, you have to pay for it even if it doesn’t work for you.

What’s the Verdict on Le Derme Luxe as a Wrinkle Cream?

Based on ingredients alone, Le Derme Luxe is probably a pretty effective wrinkle cream. DMAE, alpha lipoic acid, and female hormones are all scientifically established as wrinkle reducers. Le Derme Luxe’s efficacy is confirmed by the few available consumer reviews.

However, the mandatory membership program associated with buying Le Derme Luxe is much less appealing than the skin cream itself. I prefer to buy wrinkle creams at my own pace, and I appreciate companies that give me that option.

Unfortunately, Luxury Skin Collection doesn’t allow consumers to buy Le Derme Luxe one bottle at a time. Consequently, I’m wary of recommending Le Derme Luxe as a wrinkle cream even though it has a great ingredient profile.

References

[1] Pillai, R., M. Redmond, and J. Roding. “Anti-Wrinkle Therapy: Significant New Findings in the Non-Invasive Cosmetic Treatment of Skin Wrinkles with Beta-Glucan.” International Journal of Cosmetic Science. 27.5 (2005): 292.

[2] Farris, Patricia K. “Topical Vitamin C: A Useful Agent for Treating Photoaging and Other Dermatologic Conditions.” Dermatologic Surgery. 31 Supplement (2005): 814-18.

[3] WebMD. “Alpha-Lipoic Acid.”

[4] The Cleveland Clinic Foundation. “Understanding the Ingredients in Skin Care Products.” 2011. ClevelandClinic.org.

[5] Tadini, KA, and PM Campos. “In vivo skin effects of a dimethylaminoethanol (DMAE) based formulation.” Die Pharmazie. 64.12 (2009): 818-22.

[6] Holzer, G, E Riegler, H Honigsmann, S Farokhnia, and JB Schmidt. “Effects and side-effects of 2% progesterone cream on the skin of peri- and postmenopausal women: results from a double-blind, vehicle-controlled, randomized study.” The British Journal of Dermatology. 153.3 (2005): 626-34.

[7] Schmidt, JB, M Binder, G Demschik, C Bieglmayer, and A Reiner. “Treatment of skin aging with topical estrogens.” International Journal of Dermatology. 35.9 (1996): 669-74.

Radialabs

May 10th, 2013

radialabs160
“You will see the difference within seconds.”

Wrinkles take time to develop, so when I saw this claim for Radialabs Instant Wrinkle Reducer, I was immediately skeptical.

My skepticism was pushed further when I saw over-the-top claims regarding Instant Wrinkle Reducer’s additional abilities: increases moisturization by 440%, decreases visual appearance of fine lines up to 60%, and attacks wrinkles ”deep within source.”

However, I choose to research a product’s ingredients before I make a hasty decision about it. I hope the research I have done will give you a better idea whether Radialabs Instant Wrinkle Reducer is right for you.

Radialabs Ingredients

Radialabs is supposedly “clinically tested” to add moisture to the skin and to keep it there longer. Furthermore, it is said to prevent dry, itchy, peeling, or cracked skin via the following ingredients:

Polymoist-PS. Polymoist-PS Complex is a patented peptide blend that enhances collagen production and improves skin hydration. [1]

Vitamin E. Vitamin E is an antioxidant with protoprotective potential. According to one study, vitamin E protects the skin against sun damage. [2]

Shea Butter. A skin moisturizer, shea butter contains lipids. In one study cited in the British Journal of Dermatology, lipids “reduce skin reactions to irritants.” [3]

Mango Butter. According to researchers, mango butter significantly reduces wrinkles and skin roughness while repairing and protecting against damage. They conclude, mango butter opens “possibilities to formulate caring products for sensitive skin.” [4]

Coconut Oil. According to some experts, coconut oil repairs damaged connective tissues, while hydrating skin, making it a potential tool for preventing wrinkles. [5]

Rosa Canina Oil. With potent antioxidants including lycopene and beta carotene, rosa canina oil improves wrinkles, age spots, and weathered skin. [6]

According to one study, rose hip oil regenerates damaged skin tissues and prevents photoaging, or sun damage. Twenty women applied rose hip oil daily for four months. After just three weeks, participants saw wrinkles dissipating and sun spots fading. At the end of four months, almost all signs of aging were cleared. [7]

A Little About Radialabs

While Radialabs is not accredited by the Better Business Bureau, they are no stranger to BBB officials. More than 200 complaints for Radialabs have been filed with the Better Business Bureau, and the company has an “F” rating, which is the lowest possible.

Most customer complaints regard Radialabs’ auto-membership and monthly payments. Customers sign up for a free trial and two weeks later, they are charged $74.95. This payment recurs monthly until the customer cancels.

However, cancelling the product and asking for a refund was problematic. RipOffReport.com cites many instances when Radialabs did not redeem refunds, did not reply to customer complaints, or claimed they never received returned packages.

This is how it was when Radialabs had an official site. However, it looks as though the site has been taken down, and now the only place to purchase Radialabs is from Amazon.com.

Radialabs Advantages

• Clinically proven, natural ingredients
• Positive testimonials
• Safe for sensitive skin

Radialabs Disadvantages

• Expensive
• Ingredients and concentrations unlisted
• Poor company reputation
• Small bottle

Pricing

Radialabs Instant Wrinkle Reducer costs $74.95 for a 0.5 oz. bottle. When the official site was up, customers could click to sign up for a “free” trial, which cost $5.00 for shipping.

Then, 15 days after the trial order date, Radialabs charges customers $74.95 per month thereafter until they cancel. This is part of their auto-ship membership program, which many customers say they were unaware of at sign-up.

Currently, the only place to buy Radialabs Instant Wrinkle Reducer is from Amazon.com for $55.00 plus shipping.

In Review

If you have wrinkles and sun damage, Radialabs may work for you. Some ingredients are proven to diminish the look of wrinkles and sun spots. However, Radialabs isn’t the only wrinkle cream with these ingredients.

The $74.95 price tag for a half ounce bottle is alarming, and therefore, I cannot recommend Radialabs. Instead, I recommend finding a wrinkle cream with similar ingredients and a better price tag.

References

[1] “Benefits of Polymoist-PS Complex.” Available from: http://luvyourskin.org/benefits-of-polymoist-ps-complex/

[2] Offord E, Gautier J, Avanti O, Scaletta C, Runge F, Kramer K, Applegate L. “Photoprotective potential of lycopene, B-carotene, vitamin E, vitamin C and carnosic acid in UVA-irradiated human skin firbroblasts.” Free Radical Biology and Medicine. June 15, 2002. Volume 22, Issue 12. Pages 1293-1303. Available from: http://www.sciencedirect.com/science/article/pii/S0891584902008316

[3] Loden M, Andersson C. “Effect of topically applied lipids on surfactant-irritated skin.” British Journal of Dermatology. February 1996. Volume 134, Issue 2, pp 215-220. Available from: http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2133.1996.tb07604.x/abstract

[4] Mandawgade SD, Patravale V. “Formulation and Evaluation of Exotic Fat Based Cosmeceuticals for Skin Repair”. Indian Journal of Pharmaceutical Science. 2008 Jul-Aug;70(4):539-542. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792546/

[5] Kim Evans. “Natural Ways to Get Rid of Wrinkles.” NaturalNews.com. March 21, 2012. Available from: http://www.naturalnews.com/035309_wrinkles_exfoliation_coconut_oil.html

[6] “Remove Wrinkles with Rose Hip Seed Oil.” Smart Living Network. Available from: http://www.smartlivingnetwork.com/senior-health/b/remove-wrinkles-with-rose-hip-seed-oil/

[7] “The Components Responsible for the Effectiveness of Rose Hip Oil.” Study by: Dr. Bertha Pareja, Principal Professor, Faculty of Pharmacology and Biochemistry at University of San Marcos, Lima, Peru. Dr. Horst KehI, School of Pharmacology at University of Missouri, Kansas City, Missouri. Available from: http://www.abateit.com/science2.htm.

Flawless Effect

May 9th, 2013

auravie-logo-160

According to advertisements, Flawless Effect works instantly, removing the appearance of wrinkles and providing results that will “last all day long.”

Supposedly, Flawless Effect targets multiple signs of aging: tightening skin around the eyes, eliminating puffy bags and dark circles, and removing wrinkles, crow’s feet, and laugh lines.
And according to a clinical study, Flawless Effect is “proven” to work!

However, over-the-top advertising should always be taken with a grain of salt. To sort the fact from fiction, I researched Flawless Effect’s formula.

The Active Ingredients of Flawless Effect

Flawless Effect’s formula provides the following active ingredients intended to eliminate wrinkles.

Retinol is a fat-soluble vitamin A form proven to reduce the appearance of wrinkles. In a 2007 clinical study on 36 elderly subjects, researchers found retinol smooths wrinkles after 4 weeks.[1]

Tocopherol is available in 3 forms: tocopherol sorbate, a-tocopherol, and y-tocopherol. Studies indicate tocopherol sorbate is the most effective against UV rays and photodamage.[2][3] However, it’s unknown what type of tocopherol is found in Flawless Effect.

Ascorbyl Palmitate is an ascorbic acid variant, otherwise known as vitamin C.[4] Vitamin C is proven to protect and improve skin as an antioxidant.[5]

In 2008, researchers observed vitamin C’s effects on of 10 subjects over the course of 12 weeks. When applied topically, vitamin C significantly minimized wrinkling.[6]

While these results are promising, keep in mind the study only featured 10 test subjects. This is not a large enough sampling to determine vitamin C’s full effects.

Lecithin is a fat containing phosphatidylserine, a phospholipid component proven to improve skin health and reduce wrinkles.[7]

A 2013 clinical study on 63 individuals over 12 weeks shows phosophatidylserine increases moisture, enhances thickness, and reduced wrinkles.[7].

However, the phosophatidylserine used in the study came from soy lecithin, and it is unknown whether Flawless Effect uses soy-based lecithin.[7] Consequently, it’s impossible to tell if Flawless Effect produces results similar to the study.

A Note on Flawless Effect’s Clinical Study

Flawless Effect’s website claims a clinical study “proves that Flawless Effect works!” However, the results of this “clinical study” are questionable.

It’s unknown where and when this study took place, how many people were involved, or even the title of the study.

In addition, it appears this study has not been published in a peer reviewed scientific journal.

Merely claiming an unnamed study proves your product is 100% effective is not persuasive. It would be helpful for Flawless Effect to provide more information about this “clinical study” they cite to.

Will Flawless Effect Cause Side Effects?

For most people, Flawless Effect ingredients appear to be safe.

However, topical retinol causes skin irritation, dryness, and redness in those sensitive to vitamin A.[8]

Recommended Usage

Flawless Effect is easy to apply and to use regularly. Also, it can be used in conjunction with your favorite moisturizers and makeup, so long as you apply Flawless Effect first.

To start, wash your face with lukewarm water and mild soap to remove impurities and cleanse your pores. Then, pat dry with a soft towel.

Apply a small amount of Flawless Effect along your wrinkles, using sweeping motions as you do so. Gently patting or tapping the applied area stimulates blood flow and supposedly enhances the effects.

Allow Flawless Effect to dry fully by waiting at least 90 seconds before applying additional cosmetics.

Purchasing Flawless Effect

Currently Flawless Effect can only be purchased directly from the company at FlawlessEffect.com. The site sells a 15 ml tube for $98.37 plus $4.95 shipping and handling. This price includes a free sample of Flawless Effect’s Rejuvenating Eye Cream.

A review of Flawless Effect’s “privacy policy” reveals purchasing the product enrolls you into the “Flawless Effect Convenient Elite Autoship Program.”[9] This program sends you a monthly Flawless Effect supply for $98.37. The program can be cancelled by contacting customer service at customercare@flawlesseffect.com.[9]

Is Flawless Effect Worth a Try?

Flawless Effect’s formula contains ingredients proven to improve skin health and wrinkles. Consequently, it’s possible Flawless Effect will work for you.

However, individual ingredient dosage is not provided, making it difficult to determine how effective the formula is.

Additionally, there is little clinical evidence the ingredients minimize wrinkles within 90 seconds as Flawless Effect claims.

Considering the expensive auto-ship program and unproven ingredients, I don’t feel comfortable recommending Flawless Effect at this time. But what do you think?

Feel free to share your thoughts on Flawless Effect below!

References

[1] Kafi, Reza, et al. “Improvement of naturally aged skin with vitamin a (retinol).” Archives of Dermatology, 143.5 (2007): 606. http://archderm.jamanetwork.com/article.aspx?articleid=412795

[2] Konger, Raymond L. “A new wrinkle on topical vitamin E and photo-inflammation: mechanistic studies of a hydrophilic γ-tocopherol derivative compared with α-tocopherol.” Journal of Investigative Dermatology, 126.7 (2006): 1447-1449. http://www.nature.com/jid/journal/v126/n7/full/5700308a.html#bib8

[3] Jurkiewicz, Beth Anne, et al. “Effect of topically applied tocopherol on ultraviolet radiation-mediated free radical damage in skin.” Journal of Investigative Dermatology, 104.4 (1995): 484-488. http://www.nature.com/jid/journal/v104/n4/abs/5610918a.html

[4] Environmental Working Group. “Ascorbyl Plamitate (Vitamin C Palmitate.” Accessed 5.07.2013. http://www.ewg.org/skindeep/ingredient/700555/ASCORBYL_PALMITATE_(VITAMIN_C_PALMITATE)/

[5] Jurkovic, Polona, et al. “Skin protection against ultraviolet induced free radicals with ascorbyl palmitate in microemulsions.” European Journal of Pharmaceutics and Biopharmaceutics, 56.1 (2003): 59-66. Skin protection against ultraviolet induced free radicals

[6] Jurkovic, Polona, et al. “Skin protection against ultraviolet induced free radicals with ascorbyl palmitate in microemulsions.” European Journal of Pharmaceutics and Biopharmaceutics, 56.1 (2003): 59-66. Double-blind, half-face study on topical vitamin C

[7] Choi, Hee-Don, et al. “Effect of soy phosphatidylserine supplemented diet on skin wrinkle and moisture in Vivo and clinical trial.” Journal of the Korean Society for Applied Biological Chemistry, 56.2 (2013): 227-235.http://link.springer.com/article/10.1007/s13765-013-3012-1

[8] Mayo Clinic. “Vitamin A (retinol).” Accessed 5.07.2013. http://www.mayoclinic.com/health/vitamin-a/NS_patient-vitamina/DSECTION=safety

[9] FlawlessEffect.com. “Privacy Policy. . .” Accessed 5.07.2013. https://www.flawlesseffect.com/terms.html

Vivexin

May 8th, 2013

vivexin

According to supplement company Speedwinds Nutrition, there are 3 keys to improving the tricky under-eye area: brightening dark circles, “de-puffing” bags, and erasing fine lines and wrinkles. And if you listen to Speedwinds, Vivexin is the product to do it.

Vivexin is a face cream specifically designed to tackle skin problems around the eyes. With patented ingredients and a 90-day money-back guarantee, Speedwinds certainly presents a convincing case for its product.

However, I never take any company at its word. Before I recommend Vivexin, I want to see to see what’s really going on with this relatively popular face cream.

Does Vivexin Use Quality Ingredients?

Speedwinds doesn’t give us a look at Vivexin’s ingredient label, instead choosing to highlight 3 ingredients in the Vivexin formula.

As these are the only ingredients mentioned on Vivexin.com, it’s safe to assume these are the core ingredients in the formula. Let’s take a look at what they are and what they do for the under-eye area.

Haloxyl

Haloxyl is a patented blend of potassium, glycerin, and several peptides. Said to eliminate dark circles, Haloxyl heals leaky capillaries close to the skin that darken pigmentation.

Haloxyl was developed by the Taber Company and is included in several supposedly “high end” facial creams. Its popularity stems from a study in which subjects using Haloxyl saw a 70% improvement in under-eye appearance in less than 2 months [1].

While these results seem exciting, it’s difficult to trust them entirely because the study was funded by the Taber Company itself and has not been replicated or published in a scientific journal.

Eyeliss

Another patented ingredient, Eyeliss is a combination of 3 peptides developed and marketed by Sederma. According to Sederma, Eyeliss reduces dark circles and under-eye bags. In the definitive study, Eyeliss reduced under-eye puffiness by 65% [2].

Like the Haloxyl study, the study on Eyeliss was financed by developers, making its findings slightly questionable. However, its continued use in the skincare industry seems to signify these findings weren’t far off the mark.

Matrixyl

While Haloxyl and Eyeliss treat discoloration and bags under the eyes, Matrixyl is a bit more powerful in that it clears up fine lines and wrinkles in the eye area. Matrixyl combines several peptides to stimulate collagen production, plump the skin, and reduce wrinkle depth.

In the Matrixyl study—again, a study financed by manufacturers—Matrixyl led to a 350% increase in collagen production. Subjects using Matrixyl also saw a 39% reduction in wrinkle depth and a 17% reduction in skin roughness [3].

On its face, the Vivexin formula is fairly impressive. Each of its 3 core ingredients is well-known and often used in the skincare industry, and each is backed by scientific studies. Though these studies may not be the most reliable, it’s nice to find at least some research done on individual ingredients.

However, the fact Speedwinds doesn’t give us any more information on the Vivexin formula concerns me. There could be only small doses of each active ingredient in Vivexin, with the gaps in the formula filled by common ingredients like water and glycerin.

This leaves me uncertain as to whether or not Vivexin works.

Do Customers Like Vivexin?

Because Speedwinds doesn’t tell us much about the Vivexin formula beyond its 3 main ingredients, we need to turn to reviews written by past customers to ascertain whether Vivexin is effective.

Vivexin reviews on Amazon.com send mixed messages. With a 3.5/5-star rating based on 7 reviews, Vivexin appears as an average product that works well for some users and not so well for others.

The individual reviews bear this out. While 3 customers gave Vivexin a 5-star rating, 3 more assigned it 3 stars. The final reviewer was entirely dissatisfied with Vivexin and gave it a 1-star rating.

Unfortunately, there doesn’t seem to be any rhyme or reason as to who has positive experience with Vivexin and who does not. There is a common theme in 3-star reviews, however. These users say that while Vivexin left skin feeling smooth, it didn’t deliver on its advertised results.

Here’s a look at what they had to say:

“Left my skin feeling very smooth, and very moisturized at first, but didn’t last long enough.. Not intense enough for my dry, baggy under-eye skin. I used the rest of it up as a face lotion, which I really liked for face lotion, but not for over a dollar per pump.”—Moxynika

“I liked the texture and felt the lines under my eyes were softened. The gel did nothing to reduce the dark circles which was my reason for buying this product.” –Adrian

Only one person was completely unhappy with Vivexin and saw no positive changes.

I used this eye gel exactly as directed and saw not a bit of difference around or even near my eyes. I do not believe any of these so call creams work for lines or help you to look younger. They are being sold at high prices just so you think it is doing the job.—polkadot

Those users who gave Vivexin 5 stars said it did nearly everything it was advertised to and appreciated its relatively low price.

What can we take from all this? Vivexin is a gamble. It works for some and not for others, and there doesn’t seem to be a way to predict who will fall into each category.

How Much Does Vivexin Cost?

While users who liked Vivexin were pleased with its price, I still consider Vivexin rather expensive for an under-eye cream.

Here’s the pricing structure on Vivexin.com:

1 bottle: $59.95
2 bottles, plus 1 free bottle: $119.95
4 bottles, plus 2 free bottles: $199.95

Shipping is $5.95 within the United States and Mexico, and $11.95 internationally, so be sure to factor those prices in when evaluating Vivexin.
Unfortunately, Speedwinds Nutrition doesn’t distribute Vivexin wholesale, so there are no other Vivexin retailers. You can find a small discount on Amazon, but Speedwinds is still the official seller here.

Speedwinds attempts to take some of the gamble out of Vivexin’s high price by offering a 90-day money-back guarantee. However, customers report getting a refund is difficult, and often only part of their original purchase is refunded.

What About the Vivexin “Free Trial?”

Another thing to keep in mind when purchasing Vivexin is to avoid the free trial advertised on Vivexin.com and through pop-up ads elsewhere online.

While the free trial may seem like a great deal, there are aspects not explicitly advertised that cause problems for many customers.

Most people sign up for the free trial offer under the assumption they’ll receive a 2-month supply of Vivexin for the cost of shipping ($5.95).
However, Speedwinds also automatically enrolls people signing up for the free trial offer in an auto-ship program that charges users $89.00 each month for 2 new Vivexin bottles.

When customers try to cancel their membership, they’re told they can return products for a partial refund. However, by the time their membership is canceled, the average customer has already lost $249.91 according to estimates from ScamBook.com [4].

Issues with Speedwinds’ free trial offer have led to $19,079.34 in unresolved damages and 111 complaints on file with the Better Business Bureau [5].
Knowing this, I recommend avoiding the Vivexin free trial offer. Unless you plan to use Vivexin continuously for several months, there’s no benefit to being enrolled in Speedwinds’ auto-ship program.

Should You Try Vivexin?

If Vivexin were less expensive and not attached to a deceptive free trial offer, I might recommend giving it a try. After all, it contains quality ingredients and seems to work for about half of users.

However, if you’re in the half of customers that don’t experience many positive benefits from Vivexin, $60 per bottle is too much to pay. And because there’s no way to know beforehand if Vivexin will work for you, I don’t recommend taking this chance.

References

[1] Taber Co. February 2006. Breakthrough Biotechnology combines with Scandinavian Botanicals to create Naked Glow “The Eye Lift:” Illuminating Collagen Building Anti-Wrinkle Eye Treatment Dark Circle Reducer & Skin Fortifier. Accessed 3 May 2013. http://www.tabercoinc.com/press/2006TheEyeLift-release.pdf.

[2] Lucas Meyer Cosmetics. Homeosta-Sea Homeo-Age. Innovadex.com. Accessed 2 May 2013. http://www.innovadex.com/PersonalCare/Detail/4501/124817/HOMEOSTA-SEA-HOMEO-AGE.

[3] Lupo, Mary P. and Anna L. Cole. 2007. Cosmeceutical peptides. Dermatologic Therapy: Vol. 20, Issue 5.

[4] Scambook.com. Vivexin Company Details. Accessed 3 May 2013. http://www.scambook.com/company/reports/36464/Vivexin.

[5] Better Business Bureau. Speedwinds Nutrition. Accessed 3 May 2013. http://www.bbb.org/oregon/business-reviews/health-and-diet-products-retail/speedwinds-nutrition-in-portland-or-37005337.

Prodermagenix

May 6th, 2013

Prodermagenix 160From fine lines to wrinkles, from dark spots to puffiness, Prodermagenix is a non-prescription skin treatment said to cure them all.

For women who want younger looking skin and a chance to age gracefully, Prodermagenix’s promises are enticing. However, Prodermagenix’s anti-wrinkle benefits might not outweigh the risks it poses for delicate skin health. As one of the most sensitive organs, skin often reacts adversely to even mild irritants.

Is Prodermagenix a gentle but powerful wrinkle reducer? I investigated Prodermagenix to reveal the truth beneath the advertising.

The Formula: Ingredients

Normally, researching a product’s ingredients is the best way to determine its effectiveness. Unfortunately, this method isn’t possible with Prodermagenix. For some reason, Prodermagenix’s makers haven’t revealed the ingredients in their anti-wrinkle serum.

However, scattered around Prodermagenix.com are references to the following ingredients which likely contribute to Prodermagenix’s effectiveness.

Matrixyl. Matrixyl is a trademarked peptide molecule that encourages skin to produce collagen, elastin, and other fibrous connective tissues. So far, research indicates Matrixyl is as effective as retinol at reducing wrinkles. [1]

Hyaluronic Acid. Hyaluronic acid is a major component in young skin, but it decreases over time. [2] A recent study found hyaluronic acid with a low molecular weight improves skin elasticity, moisture, and wrinkle depth. [3]

Retinol. Retinol is an effective treatment for sun damage and some skin aging. But, some wrinkle creams with retinol do not contain enough to be effective. [4]

Vitamin C. Vitamin C benefits skin by decreasing wrinkles, age spots, and sun damage. However, vitamin C might benefit skin more when taken orally than when applied topically. [5]

Vitamin E. Vitamin E helps aging skin retain moisture. Products need at least 1% vitamin E to create noticeable results. [6] It’s unclear how much vitamin E is in Prodermagenix.

Prodermagenix’s ingredients seem to either fight wrinkles directly or supply some additional skin health benefits. Consequently, Prodermagenix probably decreases some wrinkles.

Even so, Prodermagenix’s overall efficacy cannot be determined because the makers don’t provide any information about ingredient concentration.

The Comments: Consumer Feedback

Prodermagenix.com presents comments from two Prodermagenix users.

The first is Karen, who looks to be quite young from the picture beside her comment. Karen describes her Prodermagenix experience like this:

“After just a few days, I could already see that my skin looked firmer and wasn’t near as dry. After 3 weeks, my wrinkles seemed plumped up and not so deep and I received comments about how good I looked. I love, love, love, this product.”

The second reviewer is Elise, a more mature woman. Elise had this to say about Prodermagenix:

“My skin felt so fresh faced and young from the first use, but after about two weeks other people were noticing. But, the real proof? Reuniting with old friends after 20 years. My children and coworkers mentioned how much younger I looked than my old friends.”

Karen and Elise’s comments certainly make Prodermagenix sounds like a miraculous anti-wrinkle treatment. However, these two women hardly represent every skin type or degree of skin health. Others might experience little to no improvement in wrinkles with Prodermagenix.

The Precautions: Potential Side Effects

Most Prodermagenix ingredients should cause little to no skin irritation. Only retinol is strongly associated with causing side effects. These include peeling, dryness, redness, itching, acne, and sun sensitivity. [7]

The Science: Clinical Trials

The product website lists several numbers to prove how effectively Prodermagenix reduces wrinkles. Reportedly, some Prodermagenix ingredients produced the following results in studies:

• 24% lower wrinkle volume
• 46% decrease in main lines density
• 16% reduction in skin roughness
• 50% wrinkle surface diminished

Unfortunately, the studies that produced these results aren’t cited. Furthermore, Prodermagenix’s makers don’t explain this terminology or how these factors are measured.

In addition, Prodermagenix itself doesn’t seem to have any clinical trials. Hence, Prodermagenix may not produce the same results as its individual ingredients did in these trials.

The Directions: How to Use It

Using Prodermagenix is a 3-step process. First, wash and dry your face. Second, apply Prodermagenix. Third, allow Prodermagenix to dry before applying additional skincare products or makeup.

The Price: Overall Value

According to Prodermagenix.com, the retail price is $99.95. For customers who like to try before they buy, Prodermagenix.com provides a 14-day trial bottle.

However, this trial option only lasts for 18 days from the date of purchase. After 18 days, customers are charged for the trial bottle and enrolled in an auto-ship program. This auto-ship program means Prodermagenix is shipped every 30 days for the price of $89.95 plus shipping.

While these terms are clearly delineated on the website, they aren’t disclosed prominently. Consequently, I doubt most buyers are aware of the auto-ship program or the limitations on the trial bottle.

The Verdict: To Buy or Not to Buy?

Ingredients-wise, Prodermagenix seems like a moderately effective wrinkle cream. Matrixyl, hyaluronic acid, and retinol are all linked with reversing signs of aging, particularly wrinkles. Consumer comments further confirm Prodermagenix’s effectiveness, although it would be better if more reviews were available.

However, a high price tag and the limited-time trial offer detract from Prodermagenix’s wrinkle-fighting abilities. Since it lacks clinical testing to justify its price, Prodermagenix may not be the best value wrinkle cream available.

References

[1] ErinP. “Palmitoyl Pentapeptide-4.” TruthInAging.com. 2009 May 14.

[2] The Cleveland Clinic Foundation. “Understanding the Ingredients in Skin Care Products.” 2011. ClevelandClinic.org.

[3] Pavicic, T, GG Gauglitz, et al. “Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment.” Journal of Drugs in Dermatology. 10.9 (2011): 990-1000.

[4] “Skin wrinkles and blemishes – Treatment.” University of Maryland Medical Center. 2008 Dec 30.

[5] Watson, Stephanie. “Vitamins and Supplements Lifestyle Guide: Skin Care Vitamins and Antioxidants.” WebMD.com. 2012 Apr 24.

[6] Repinski, Karyn. “5 Best Vitamins For Beautiful Skin.” Prevention. 2012 Nov. Prevention.com.

[7] “What Are Retinol Side Effects?” WiseGeek.org.

Xtend-Life

May 6th, 2013

xtendlife

It’s not often I run across a company like Xtend-Life that creates multiple supplements under the same name. Most companies prefer to focus on 1 or 2 products, or choose to market several under different company names to limit liability and potential damages.

So when I see a flourishing company like Xtend-Life that sells multiple products with many different focuses, I’m curious about what they have to offer.

Specifically, I want to know if Xtend-Life sells any anti-aging products and if they’re as popular as their brand name.

What Kinds of Products Does Xtend-Life Make?

Xtend-Life is a New Zealand-based company run by fitness fan Warren Matthews. Xtend-Life was founded in 2000 after Matthews turned 50 and began looking for natural ways to slow the aging process.

The result is more than 30 Xtend-Life products designed to tackle the physical concerns of aging. These products include multivitamins, heart supplements, colon cleanses, sexual enhancement supplements, and natural treatments for arthritis and other joint problems.

Xtend-Life is relatively successful and has extended its business to offices in Australia and Thailand. The company’s attempt to break into the U.S. market is ongoing, and only time will tell if Xtend-Life products are impressive enough to gain an American audience.

Does Xtend-Life Do Anything For Wrinkles?

Under the anti-aging umbrella, Xtend-Life carries a few products specifically designed to combat wrinkles.

The company’s skin-care line boasts 3 products said to decrease signs of aging like wrinkles and under-eye circles and bags. These products are found both in the men’s and women’s sections of the Xtend-Life website.

Here’s a look at what they’re said to do.

Age Defense Active Day Cream

Age Defense Active Day Cream is Xtend-Life’s all-inclusive skin-care formula. Said to reduce fine lines and wrinkles, Age Defense Active Day Cream stimulates collagen and elastin production. This product also contains hyaluronic acid to keep skin smooth and moisturized.

While Age Defense Active Day Cream delivers some visible results quickly, Xtend-Life says it’s primarily meant to work over a longer time period.

Restorative Night Cream

Restorative Night Cream is meant to work alongside Age Defense Active Day cream to continue anti-aging efforts into the night. Meant to promote greater collagen and elastin production, Restorative Night Cream is said to rejuvenate skin cells and reduce wrinkle depth and visibility.

Like Age Defense Active Day Cream, Restorative Night Cream also contains hyaluronic acid to smooth and moisturize skin. Xtend-Life says Restorative Night Cream also prevents free radicals from causing oxidation, which leads to wrinkles and sagging skin.

Eye Contour Serum

This product specifically treats the eye area. Said to eliminate dark circles, bags, and wrinkles around the eyes, Eye Counter Serum tackles the most common problem area in both men and women.

According to advertisements, noticeable differences start appearing in less than a month.

These products are exactly the kind of products most people are looking for when they seek an over-the-counter wrinkle treatment. The Xtend-Life products probably won’t provide highly-visible, lasting benefits, but they will improve appearance steadily during use.

That is, they will if they work. To determine that, I need to look at the common ingredients in Xtend-Life products.

Does Xtend-Life Use Quality Ingredients?

Xtend-Life provides an ingredient label on Xtend-Life.com for each of its products, including the 3 I’ve just covered.

For now, however, I’ll analyze some of the more commonly-used ingredients in these wrinkle creams. This way, you can get an idea of the overall quality of Xtend-Life products.

Eyeliss

A patented ingredient developed and marketed by Sederma, Eyeliss is a combination of 3 peptides frequently included in wrinkle creams. Said to boost collagen production and strengthen under-eye capillaries, Eyeliss reduces both dark circles and fine lines surrounding the eyes. In the Eyeliss study, subjects using Eyeliss also experienced a 65% reduction in under-eye puffiness [1].

I’m always hesitant to trust manufacturer-financed studies like this one, but Eyeliss’s continuing popularity makes me think there’s something to this ingredient after all.

Haloxyl

Like Eyeliss, Haloxyl is a patented compound of peptides and other ingredients. Developed by the Taber Company, Haloxyl is said to eliminate under-eye circles by healing leaky capillaries that cause discoloration.

In the Haloxyl study, Haloxyl improved under-eye appearance by 70% in less than 2 months [2]. Again, this study was financed by the manufacturers so it’s hard to trust completely.

Homeo Age

Homeo Age is included in all 3 of Xtend-Life’s wrinkle creams. Developed by Lucas Meyer Cosmetics, Homeo Age is based on brown algae and contains vitamins and minerals that stimulate cell growth. Supposedly, this reduces eye wrinkles.

In the definitive study, Homeo Age increased cell production by 25% [3]. Unfortunately, Homeo Age is not as widely used as Haloxyl or Eyeliss, so it’s hard to tell if these claims are valid or just a product of a financially-interested researcher.

Vitamin E

Vitamin E is a common ingredient in natural skin care products due to its potent anti-aging effects. Said to reduce retinol levels and protect the skin from photoaging, vitamin E is largely a preventative ingredient. It’s especially important if you spend a lot of time in the sun.

In one study, vitamin E successfully defended mouse skin against UVA and UVB radiation for nearly 5 hours [4]. Unfortunately, these benefits have not yet been tested in humans.

Xtend-TK

Xtend-TK is an ingredient developed by Xtend-Life itself. Like Homeo Age, it’s included in all Xtend-Life skin care products.

Xtend-TK is based on keratin, the most abundant protein in human skin. Keratin is vital for keeping skin moisturized and producing new skin cells, which Xtend-Life says may decrease wrinkle depth. However, for some people, extra keratin may not be desirable.

As many as 1 in 4 people suffer from keratosis pilaris, an excess of keratin that results in red, rough bumps on the skin. Adding additional keratin with Xtend-TK may exacerbate the condition [5].

Shea Butter

You may be familiar with shea butter as a natural emollient in lotions and other moisturizers. In Xtend-Life products, shea butter absorbs lightly the skin to deliver moisture and decrease inflammation. In terms of anti-aging, shea butter is also said to reduce blemishes, scars, and discolorations in the skin [6]. This may play some role in reducing the appearance of wrinkles.

There’s a lot to like about the ingredients in Xtend-Life products. Several are tested and used extensively in the anti-aging industry. Others have important moisturizing properties that round out the formula.

However, these ingredients are only effective in certain amounts. And while Xtend-Life tells us exact ingredient amounts in other company products, it doesn’t divulge individual amounts in its skin-care products.

This makes it difficult to judge effectiveness, which makes trying Xtend-Life products a bit of a gamble.

Are the Xtend-Life Wrinkle Creams Affordable?

Based on the several patented ingredients in Xtend-Life products, I was prepared to see high prices for the company’s wrinkle creams. Fortunately, that’s not the case.

While other products that include ingredients like Haloxyl and Eyeliss retail for $65 to $75 per bottle, Xtend-Life products are remarkably more affordable.

Here’s a look at the retail prices for each product I examined:

Age Defense Active Day Cream: $36.75 per 1.7-ounce bottle
Restorative Night Cream: $38.75 per 1.7-ounce bottle
Eye Contour Serum: $37.00 per 0.5-ounce bottle

Before you exult too much over this discount, however, remember Xtend-Life products ship from New Zealand and international shipping is likely expensive. Make sure to check the total price, including shipping, before you compare Xtend-Life products with other wrinkle creams closer to home.

Is Xtend-Life a Good Company for Anti-Aging Products?

There’s nothing particularly wrong with Xtend-Life products. In fact, with an affordable price and high-quality ingredients, there is plenty to like.
However, the absence of information on individual ingredient quantities concerns me. You can take the risk with Xtend-Life or pay a little extra for a product that discloses all the relevant information on its formula.

References

[1] Sederma. 2000. Gel for Anti Puffy Eyes with Eyeliss. AuraCanad.com. Accessed 3 May 2013. http://www.auracanada.com/uploads/files/Eyeliss.pdf.

[2] Taber Co. February 2006. Breakthrough Biotechnology combines with Scandinavian Botanicals to create Naked Glow “The Eye Lift:” Illuminating Collagen Building Anti-Wrinkle Eye Treatment Dark Circle Reducer & Skin Fortifier. Accessed 3 May 2013. http://www.tabercoinc.com/press/2006TheEyeLift-release.pdf.

[3] Lucas Meyer Cosmetics. Homeosta-Sea Homeo-Age. Innovadex.com. Accessed 2 May 2013. http://www.innovadex.com/PersonalCare/Detail/4501/124817/HOMEOSTA-SEA-HOMEO-AGE.

[4] Beijersbergen van Henegouwen, G.M. , H.E. Junginger, and H. de Vries. 1995. Hydrolysis of RRR-alpha-tocopheryl acetate (vitamin E acetate) in the skin and its UV protecting activity (an in vivo study with the rat). Journal of Photochemistry and Photobiology: Vol. 29, Issue 1.

[5] Mayo Clinic Staff. Keratosis pilaris. Accessed 6 May 2013. http://www.mayoclinic.com/health/keratosis-pilaris/DS00769.

[6] Rutland, Sarah. 2013. Does Shea Butter Help Scars Fade? Accessed 3 May 2013. http://health.howstuffworks.com/skin-care/problems/treating/shea-butter-help-scars.htm.

Envision Beauty

May 3rd, 2013

Envision Beauty

Envision Beauty’s 5-in-1 Facial Moisturizer is designed to be a total skincare system. Instead of spending hundreds of dollars on multiple skin care products, women can allegedly use Envision Beauty to replace five of their most essential skin care products, including their wrinkle cream.

While Envision Beauty sounds like a convenient skin care system, I’m skeptical about its wrinkle fighting power. After all, Envision Beauty is primarily a moisturizer. Usually reducing set-in wrinkles requires more than just moisturizing lotion.

Before you replace your current wrinkle cream with Envision Beauty, take a closer look at what’s inside.

Ingredient Breakdown

Envision Beauty uses a dozen ingredients to achieve its supposed skincare benefits. However, I’ll focus on ingredients most likely to reduce wrinkles.

DMAE. Several studies show DMAE is a promising anti-wrinkle ingredient. Applying a 3 percent DMAE facial gel for 16 weeks reduced both prominent forehead wrinkles and finer eye wrinkles. [1] However, it remains unclear whether DMAE is more effective than other common wrinkle treatments.

Alpha-Lipoic Acid. Alpha-lipoic acid has both antioxidant and anti-inflammatory effects on skin. Women who used a 5 percent ALA cream for 12 weeks noticed 50 percent decrease in skin roughness. [2]

Hyaluronic Acid. In injectable form, hyaluronic acid is a safe and effective wrinkle filler. But, dermatologists aren’t sure it provides the same benefits when applied topically. [3]

Goji. Goji berries and goji berry juice both contain antioxidants that may provide anti-aging effects. Mice who drank goji berry juice showed reduction in sunburn swelling. [4] Further skin benefits from goji remain to be proven.

Acai. Acai oil contains lots of hardy antioxidants that do not easily breakdown over time. Antioxidants definitely benefit skin, but it’s not clear how acai’s specific antioxidants affect skin health. [5]

Vitamin A. Vitamin A has small molecules that seep into skin and attach to collagen and elastin. This property of vitamin A makes it an excellent wrinkle reducer. [6]

Vitamin C. Vitamin C stimulates collagen production. One study showed topically applied vitamin C is especially effective at increasing collagen in postmenopausal women. [7]

Some Envision Beauty ingredients are very strongly linked to wrinkle reduction. But, others like hyaluronic acid and goji aren’t proven to improve wrinkles at all when applied directly to the skin.

Further, the efficacy of these ingredients is hard to determine because Envision Beauty’s website provides no additional information about strength or amounts.

Customer Comments

Envision Beauty’s website doesn’t have any consumer testimonials. While obviously these are not required, they’re sometimes helpful for indicating how much confidence a company has in its product.

Although Envision Beauty can no longer be purchased on Amazon.com, there are a few Envision Beauty reviews still on the site.

Positive reviewers noticed the following benefits:

• No breakouts
• Works day and night
• Less oily skin
• Replaces multiple products

These women seemed delighted with Envision Beauty. Even so, one of them urged women to allow three months before judging overall results.

Plus, Envision Beauty had just as many negative reviews as positive ones. Here are some of the customer complaints:

• No SPF
• Expensive
• Not an adequate replacement for other beauty products
• Unexpected charges

Overall, these reviews suggest Envision Beauty may or may not provide the multiple benefits its ads promise. Disappointingly, though, they say nothing about Envision Beauty’s power as a wrinkle cream.

Purchase Price and Conditions

Envision-Beauty.com’s webpage doesn’t prominently list the price. In fact, the only hint at a potential price on the homepage is hidden in a chart comparing Envision Beauty and two other facial care products.

After inputting some personal information, I discovered Envision-Beauty.com’s price: $89.95 for a 1 ounce bottle. SkinCareDelivery.com offers a slightly lower price: $71.97.

The terms and conditions on Envision-Beauty.com describe a money-back guarantee attached to Envision Beauty purchases. Customers not satisfied with Envision Beauty have 30 days to return used and unused product for a full refund.

The terms and conditions also describe Envision Elite as “an optional monthly delivery program.” By signing up for this program, consumers are promised discounts and automatic monthly shipments of Envision Beauty.

Usage Directions

Unfortunately, Envision Beauty’s website lists no instructions for using this product. Since it is said to replace both makeup base and night treatment, it’s probably meant to be used both morning and night. However, this is only a guess. Better information about how much and how often to use Envision Beauty would give me greater confidence in this product.

Conclusion

As a wrinkle reducer, Envision Beauty is probably so-so. Several ingredients are proven to fight wrinkles. But, since Envision Beauty’s one product attempts to assist multiple skin problems, its wrinkle-fighting ingredients may not be strong enough.

Moreover, Envision Beauty’s website creates doubts about the integrity of the manufacturer. Concealing Envision Beauty’s price and usage directions doesn’t make this product more appealing. Plus, consumer comments about unexpected charges make me wary of purchasing Envision Beauty.

To be on the safe side, I recommend avoiding Envision Beauty.

References

[1] Grossman, R. “The role of dimethylaminoethanol in cosmetic dermatology.” American Journal of Clinical Dermatology. 6.1 (2005): 39-47.

[2] Beitner, H. “Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoageing of facial skin.” British Journal of Dermatology. 149.4 (2003): 841-9.

[3] Dawson, Alene. “Skin care’s new favorite ingredient: hyaluronic acid.” LA Times. 2010 Jun 7. Articles.LATimes.com.

[4] Reeve, Vivienne E, Munif Allanson, Sondur Jayappa Arun, Diane Domanski, and Nicole Painter. “Mice drinking goji berry juice (Lycium barbarum) are protected from UV radiation-induced skin damage via antioxidant pathways.” Photochemical & Photobiological Sciences. 9 (2010): 601-607.

[5] “Acai Berries and Acai Berry Juice – What Are the Health Benefits?” WebMD.com. 2012 Jun 23.

[6] The Cleveland Clinic Foundation. “Understanding the Ingredients in Skin Care Products.” 2011. ClevelandClinic.org.

[7] Nusgens, BV, P Humbert, et al. “Topically applied vitamin C enhances the mRNA level of collagens I and III, their processing enzymes and tissue inhibitor of matrix metalloproteinase 1 in the human dermis.” Journal of Investigative Dermatology. 116.6 (2001): 853-9.

RevitaSkin

May 2nd, 2013

revitaskin

“Get the skin you deserve,” boasts advertisements for RevitaSkin, an anti-aging cream from Dermavant Labs.

Judging by RevitaSkin’s advertising campaign, the skin you deserve is soft, moisturized, plump, and free of age spots and wrinkles. To help you get these anti-aging benefits, RevitaSkin includes peptides and herbal extracts scientifically-proven to benefit skin.

However, the tradeoff for this level of youth is $80 per bottle. That’s a steep price to pay for something that isn’t permanent. Is it worth it? I wanted to find out and I did. Keep reading to see what I discovered about RevitaSkin.

What’s in RevitaSkin?

Dermavant Labs says RevitaSkin does everything from filling in wrinkles to erasing age spots, but its effectiveness depends entirely on the ingredients in the formula. Unfortunately, Dermavant Labs doesn’t tell us much on that score.

Instead of supplying their total nutritional facts, Dermavant Labs names a few ingredients in the RevitaSkin formula. These are likely the crux of the formula, but I’d prefer to know more.

That’s because even if these ingredients are effective, manufacturers could have included numerous filler ingredients to dilute their effectiveness. Or, because we don’t know individual ingredient quantities, manufacturers could have included just tiny portions of the most effective ingredients.

Nevertheless, let’s see what RevitaSkin has to offer.

Hyaluronic Acid

Hyaluronic acid is the fluid found in joints that cushions joints and prevents conditions like osteoarthritis. When made synthetically, some researchers say it stimulates collagen production to boost elasticity and erase wrinkles.

However, the only study to validate this effect involved an oral hyaluronic acid supplement [1]. It’s not yet known if the effects would be similar in a topical supplement such as RevitaSkin.

Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide

Together, these palmitoyl peptide forms are known as Matrixyl 3000. A trademarked peptide, Matrixyl 3000 is said to stimulate collagen production, reduce wrinkles, and plump the skin.

The study often cited in relation to Matrixyl 3000 boasts a 350% increase in collagen. This led to a 39% reduction in wrinkle depth and a 17% reduction in skin roughness [2]. However, I rarely trust studies funded by the product’s manufacturer. Furthermore, these results were produced “in vivo,” meaning they involved tests in petri dishes instead of tests on human skin.

Licorice Root

While hyaluronic acid and Matrixyl 3000 attend to fine lines and wrinkles, licorice root is said to improve complexion. With the polyphenol flavonoid glabridin, licorice root inhibits the chemical processes that lead to freckles, age spots, and melisma. Unfortunately, there are only a few studies on this subject [3].

Vitamin E Acetate

A dry vitamin E form, vitamin E acetate provides all the benefits of vitamin E along with some unique moisturizing properties. Vitamin E increases retinol levels, which protect the skin from the number one cause of wrinkles and age spots: photoaging.

In one study, vitamin E acetate prevented photoaging from damaging rat skin for up to 5 hours after application [4]. Unfortunately, these results have not yet been tested in humans.

Green Tea

You already know green tea’s antioxidant content makes it a great addition to any health plan. However, the specific skin benefits related to this extract may come as a surprise.

According to researchers, green tea prevents UVA and UVB rays from damaging the skin through photoaging. Green tea also reduces fine lines and wrinkles when applied topically. In one study, both mice and humans experienced positive anti-aging benefits with green tea [5].

The ingredients in RevitaSkin are interesting and may well prove effective for some people. They have certainly shown promise in scientific studies.

However, there is still a large element of uncertainty here. Most ingredients have only been tested on animals or as an oral supplement—not as a topical cream for human skin. This casts a little doubt on RevitaSkin’s effectiveness.

Can It Cause Side Effects?

Another question many people have when considering wrinkle creams is whether it will cause any negative reactions to the skin.

Because RevitaSkin doesn’t contain any harsh chemicals ore allergens, it’s safer than most skin creams. However, it may still cause a reaction in some users with sensitive skin. Potential reactions include:

• Heat and flushing
• Redness
• Swelling
• Rash

While these side effects are possible, you can reduce their likelihood by using only a small bit of RevitaSkin at a time and avoiding facial cleansers with harsh chemicals. If you experience any concerning side effects, stop using RevitaSkin and talk to your dermatologist.

What’s the Best Way to Use RevitaSkin?

Using RevitaSkin is pretty easy. Unlike other wrinkle creams, you don’t need to use it with water or at a certain time for it to be effective. Instead, Dermavant Labs recommends using RevitaSkin twice a day on dry skin.

To apply, take a few drops of serum on two fingers and then massage it into your skin until it dissolves. When you reach problem areas, tap your fingers on your skin to stimulate blood flow and speed results.

Most customers like using RevitaSkin once in the morning and again before bed.

Is RevitaSkin Expensive?

Unfortunately, Dermavant Labs doesn’t sell RevitaSkin through third-party retailers, which means RevitaSkin is only available on RevitaSkin.com. There, you can get one bottle for $79.95 or save money by buying 2 bottles for $159.90 and get a third bottle free.

Shipping costs vary depending on your location and preferences. There’s a helpful chart on RevitaSkin.com detailing how long it takes for your order to reach you, as well as the following shipping options:

Ground, 3-5 Days: $7.95
3-Day Select, 3 Days: $9.95
2nd Day Air, 2 Days: $12.95
Next Day Air, Next Day: $22.95
To Canada, 5-15 Days: $14.95
International Shipping, 5-25 Days: $19.95

With the initial price and the additional shipping, this is a high price to pay for a wrinkle cream that depends on largely unproven ingredients. And unfortunately, it doesn’t look like Dermavant Labs offers discounts on their products.

However, if you decide to order, fill out the form on RevitaSkin.com or call customer service at 1-800-511-4356.

Is RevitaSkin Worth a Try?

RevitaSkin isn’t a bad product. Although its ingredients have not all been tested and proven effective in human subjects, they do show promise in treating skin conditions and preventing signs of aging.

However, with such a high price and no options for a discount, I can’t recommend RevitaSkin. You’d be better off looking for a product with these ingredients at a lower price.

References

[1] WebMD. 2013. Hyaluronic Acid. http://www.webmd.com/vitamins-supplements/ingredientmono-1062-HYALURONIC%20ACID.aspx?activeIngredientId=1062&activeIngredientName=HYALURONIC%20ACID.

[2] Lupo, Mary P. and Anna L. Cole. 2007. Cosmeceutical peptides. Dermatologic Therapy: Vol. 20, Issue 5.

[3] University of Maryland Medical Center. Licorice. Accessed 29 April 2013. http://www.umm.edu/altmed/articles/licorice-000262.htm.

[4] Beijersbergen van Henegouwen, G.M. , H.E. Junginger, and H. de Vries. 1995. Hydrolysis of RRR-alpha-tocopheryl acetate (vitamin E acetate) in the skin and its UV protecting activity (an in vivo study with the rat). Journal of Photochemistry and Photobiology: Vol. 29, Issue 1.

[5] Katiyar, S.K., N. Ahmad, and H. Mukhtar. 2000. Green tea and skin. Archives of Dermatology: Vol. 136, Issue 8.